Illustrative at-home sample collection for DeepGene
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Two genomes. One sample.

DeepGene Biome.

Your microbiome and your human DNA, analysed together. A deeper view of what makes your biology yours — from a single sample, collected at home.

Not just who lives in your gut.
How the two sides connect.

The microbial genome changes with your environment. Your inherited genetics provide another layer of context. DeepGene reads both in the same sample, bringing the ecosystem and the host into one report.

Your microbiome

01

Bacteria, archaea, fungi and DNA viruses. The organisms present, their functional genes and the pathways they carry — not simply a bacterial family list.

Composition · Function · Microbial pressure

Your human DNA

02

Human DNA present in the same sample is retained for analysis: inherited predispositions, fragment integrity and tissue-turnover signals relating to the gut lining.

Predisposition · DNA integrity · Tissue turnover

Deep shotgun metagenomics

Beyond a single marker gene.

Rather than reading only 16S — a bacterial barcode — shotgun sequencing samples DNA across the specimen. DeepGene uses these reads to identify organisms, measure microbial genes and analyse the human DNA alongside them.

Illustrative laboratory sequencing workflow with a sample flow cell
Illustrative sequencing workflow

Higher resolution

Species and strain-level detail where coverage permits, including genes that distinguish one strain from another.

Measured gene capacity

Functional genes are counted from sequencing reads, rather than inferred only from bacterial names.

The host stays in view

Human reads are retained for analysis, bringing your biology into the microbial picture.

Inside your DeepGene report

A deeper picture.
With the reasoning in view.

Measurements, reference ranges and evidence levels. A report to explore with your doctor — with access to the underlying data, not just a score.

Illustrative microscopy of microbial organisms

Organisms identified across bacteria, archaea, fungi and DNA viruses, with species and strain-level resolution where the sequencing data supports it. Results are placed alongside reference ranges where available.

From information to a next step

Know where to look.
Know what can change.

A more informed conversation

Bring mechanism-level context to persistent symptoms and existing conditions. DeepGene supports the discussion; it does not provide a diagnosis.

Inherited and modifiable, together

Separate genetic predisposition from microbial pathways that may change with diet, lifestyle and treatment.

A baseline to return to

A later sample can help compare your microbial profile over time. A change in a test result alone does not establish treatment benefit.

From sample to report

Simple for you. Deep in the lab.

  1. 01

    Collect at home

    One stool sample using the supplied kit. Follow its collection, stabilisation and return instructions.

  2. 02

    Sequence deeply

    Shotgun sequencing reads DNA fragments across the sample, rather than a single bacterial marker gene.

  3. 03

    Read both genomes

    The DeepGene engine combines microbial profiling, functional genes and host DNA analysis.

  4. 04

    Understand your results

    A report for you and your doctor, with measurements, references, evidence levels and the underlying data.

A deeper input. A continuous model.

The test is a starting point.
Not the whole story.

When used with Nostra, DeepGene informs NostraBiome’s own frontier biology models alongside your medical history, existing results and daily signals. The app connects that picture to personalised guidance between doctor visits.

Understand · Guide · Observe · Learn · Adapt

Discover continuous care
Nostra app showing biological state, trajectory and daily priorities
Nostra app · Illustrative biology state

Evidence, not a promise

More detail.
Clear limits.

DeepGene includes measured sequencing data and model-derived interpretations. Some mechanisms remain exploratory. Genetic predispositions, host-DNA indices and gut–organ scores should be reviewed in clinical context; they do not diagnose disease or replace established investigations.

NostraBiome describes its software as a CE-marked Class I medical device. That status applies to the software, not a claim that every DeepGene measure or health outcome is clinically validated.

Order DeepGene Biome

Two genomes.
One sample.

Order the standalone DeepGene Biome test through our secure checkout, or explore a plan with continuous Nostra care.